ID 3892 - Czepota puszysta

PL: Czepota puszysta
EN: Uncaria tomentosa (Common Name : cat's claw)
Pdf:

1.1. Utrzymanie prawidłowego stanu stawów (ID 1799, 1973, 2022, 2178, 2202, 2254, 2255, 2311, 2394, 2417, 2418, 2458, 2649, 2794, 2798, 3119, 3144, 3274, 3283, 3318, 3339, 3495, 3511, 3523, 3555, 3624, 3699, 3748, 3770, 3835, 3884, 3892, 3904, 3943, 3978, 4012, 4020, 4056, 4137, 4175)

The claimed effects are "joint health/mobility/comfort", "joints", "joint support", "helps to maintain mobility of joint during and after climacterium", "contributes to physical well-being". The Panel assumes that the target population is the general population for all claims except for ID 3144, for which the Panel assumes that the target population is post-menopausal women.
In the context of the proposed wordings, the Panel assumes that the claimed effects refer to the maintenance of normal joints.
The Panel considers that maintenance of normal joints is a beneficial physiological effect.

2.1. Utrzymanie prawidłowego stanu stawów (ID 1799, 1973, 2022, 2178, 2202, 2254, 2255, 2311, 2394, 2417, 2418, 2458, 2649, 2794, 2798, 3119, 3144, 3274, 3283, 3318, 3339, 3495, 3511, 3523, 3555, 3624, 3699, 3748, 3770, 3835, 3884, 3892, 3904, 3943, 3978, 4012, 4020, 4056, 4137, 4175)

No human studies investigating the effects of the food(s)/food constituent(s) on the maintenance of normal joints have been provided in relation to any of the health claims evaluated in this section.
Some human intervention studies investigating the effects of the food(s)/food constituent(s) on the treatment of osteoarthrosis or (osteo)arthritis of different origin (rheumatoid arthritis, psoriatic arthritis, arthritis of infectious origin) were submitted. The Panel considers that the evidence provided does not establish that patients with osteoarthrosis or (osteo)arthritis of different origin are representative of the general population with regard to the status of joint tissues, or that results obtained in studies on subjects with osteoarthrosis or (osteo)arthritis of different origin relating to the treatment of symptoms of these diseases (e.g. erosion of articular cartilage, reduced mobility of joints) can be extrapolated to the maintenance of normal joints in the general population. Thus, for claims supported only by references to human studies on patients with osteoarthrosis or (osteo)arthritis of different origin, the Panel considers that a cause and effect relationship has not been established between the consumption of the food(s)/food constituent(s) and the claimed effect in the general population.
A number of in vitro studies were provided addressing the effects of different food(s)/food constituent(s) on human chondrocytes/cartilage explants and chondrocyte cell lines. Also, studies were provided on the relationship between the intake of the food(s)/food constituent(s) and the claimed effect in animal models of experimentally-induced arthritis. The Panel considers that the evidence provided in the animal and in vitro studies submitted is not sufficient to predict the occurrence of an effect of the food(s)/food constituent(s) on the maintenance of normal joints in vivo in humans. The Panel considers that while effects shown in animal and in vitro studies may be used as supportive evidence, human studies are required for substantiation of a claim. Thus, for claims supported by references to animal studies and/or in vitro studies only, the Panel considers that a cause and effect relationship has not been established between the consumption of the food(s)/food constituent(s) and the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the consumption of the food(s)/food constituent(s) evaluated in this section and the maintenance of normal joints.

3. Naukowe uzasadnienia wpływu na zdrowie człowieka

Most of the references provided addressed food(s)/food constituent(s) other than those for which the specific claims are proposed, and/or claimed effects unrelated to the structure and/or function of joints, bone and muscles. This literature includes general reviews on the "antioxidant" or "anti- inflammatory" properties of food(s)/food constituent(s) used in certain countries in the management of medical conditions associated with acute or chronic joint damage of either inflammatory or degenerative origin (e.g. osteoarthritis, rheumatoid arthritis, psoriatic arthritis, arthritis of infectious origin). The Panel considers that no scientific conclusions can be drawn from these references for the substantiation of the claims.

Warunki i możliwe ograniczenia stosowania oświadczenia

Leaf, flowers, thorns, bark / The equivalent of minimum 1000 mg dried plant material per day