1737.pdf

Oryginał 
Scientific Opinion on the substantiation of health claims related to flavan-3-ols and “vascular activity” (ID 1964) and “dermal activity” (ID 1965) pursuant to Article 13(1) of Regulation (EC) No 1924/2006[sup]1[/sup] EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)2, 3 European Food Safety Authority (EFSA), Parma, Italy
Słowa kluczowe: Flavan-3-ols   health claims  
ID:    1964      1965  
Produkty: Flawan-3-ol  

1. Charakterystyka żywności / składnika

The food constituents that are the subject of this opinion are single and oligomeric flavan-3-ols related to the following claimed effects: “vascular activity” and “dermal activity”. The conditions of use specify foods containing >85 % of single and oligomeric flavan-3-ols. The single flavan-3-ol (i.e. catechin and epicatechin) and oligomeric flavan-3-ol (i.e. procyanidins) content in different types of foods of plant origin is measurable by established methods, but the single versus oligomeric flavan-3-ol profile varies widely depending on the food source and may have an impact on the claimed effects.
The references provided for the scientific substantiation of these claims include narrative reviews, animal studies and human intervention studies on oligomeric proanthocyanidins, procyanidins from grape seeds, oligomeric proanthocyanidins from grape seed, pycnogenol, procyanidol oligomers, procyanidins extracted from the rhizomes of Potentilla tormentilla or from French pine bark, and “naturally-occuring” procyanidins for which the origin and composition are unknown on various health outcomes, most of them unrelated to the claimed effects.
The Panel considers that the food constituents, single and oligomeric flavan-3-ols, which are the subject of this opinion, are not sufficiently characterised in relation to the claimed effects considered in this opinion.
The Panel concludes that a cause and effect relationship cannot be established between the consumption of single and oligomeric flavan-3-ols and the claimed effects evaluated in this opinion.

Wnioski

On the basis of the data presented, the Panel concludes that:
The food constituents, single and oligomeric flavan-3-ols, which are the subject of this opinion, are not sufficiently characterised in relation to the claimed effects considered in this opinion.
A cause and effect relationship cannot be established between the consumption of single and oligomeric flavan-3-ols and the claimed effects considered in this opinion.