ID 75 - Witamina B6

PL: Witamina B6
EN: Vitamin B6
Pdf: vitamin B6

Oświadczenie (4)

Oświadczenie (2)

1. Charakterystyka żywności / składnika

The food constituent that is the subject of the health claims is vitamin B6, which is a group of compounds comprising three free forms, pyridoxine, pyridoxal, pyridoxamine, and their 5'-phosphates derivatives (PNP, PLP and PMP). Vitamin B6 occurs naturally in foods, mainly as pyridoxal phosphate (animals), pyridoxine beta-glucoside (plants) and some pyridoxyl peptides (processed foods). Vitamin B6 is a well recognised nutrient and is measurable in foods by established methods.
Vitamin B6 is authorised for addition to foods (Annex I of the Regulation (EC) No 1925/20066 and Annex I of Directive 2002/46/EC7). This evaluation applies to vitamin B6 naturally present in foods and those forms authorised for addition to foods (Annex II of the Regulation (EC) No 1925/2006, and Annex II of Directive 2002/46/EC).
The Panel considers that the food constituent, vitamin B6, which is the subject of the health claims is sufficiently characterised.

2.7. Udział w prawidłowym pozyskiwaniu energii w procesach metabolicznych (ID 75, 214)

The claimed effects are “energy and vitality” and “muscle metabolism: shares in biochemical reaction which are needed for muscle contraction”. The Panel assumes that the target population is the general population.
In the context of the clarifications provided by Member States, the Panel assumes that the claimed effects are related to energy-yielding metabolism.
The Panel considers that contribution to normal energy-yielding metabolism is a beneficial physiological effect.

3. Naukowe uzasadnienia wpływu na zdrowie człowieka

Vitamin B6 functions as a coenzyme in a variety of enzymatic reactions in the metabolism of amino acids, one-carbon units, lipids, the pathways of gluconeogenesis, haem, and neurotransmitter biosynthesis (McCormick, 2006; Mackey et al., 2006).

3.7. Udział w prawidłowym pozyskiwaniu energii w procesach metabolicznych (ID 75, 214)

Vitamin B6, as PLP, plays a dual role in the provision of glucose. Glycogen phosphorylase relies on PLP as a coenzyme in the enzymatic cleavage of glycogen that sequentially releases glucose-1- phosphate units. PLP-dependent transaminases convert gluconeogenic amino acids to alpha-keto acids to create substrates for the production of glucose (Mackey et al., 2006).
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The Panel concludes that a cause and effect relationship has been established between the dietary intake of vitamin B6 and contribution to normal energy-yielding metabolism.

4.2. Udział w prawidłowym pozyskiwaniu energii w procesach metabolicznych (ID 75, 214)

The Panel considers that the following wording reflects the scientific evidence: “Vitamin B6 contributes to normal energy-yielding metabolism”.

5. Warunki i możliwe ograniczenia stosowania oświadczenia

The Panel considers that in order to bear the claims a food should be at least a source of vitamin B6 as per Annex to Regulation (EC) No 1924/2006. Such amounts can be easily consumed as part of a balanced diet. The target population is the general population. Tolerable Upper Intake Levels (ULs) have been established for vitamin B6 in children, adolescents and adults (SCF, 2000).

Warunki i możliwe ograniczenia stosowania oświadczenia

Must meet minimum requirements for use of the claim "source of [name of vitamin/s] and/or [name of mineral/s}" as per Annex to Regulation 1924/2006. Applicable to both children and adults. Agency guidance for supplements is that products containing >10 mg of vitamin B6 should carry the label advisory statement "Long term intakes [of this amount of vitamin B6] may lead to mild tingling and numbness"