ID 74 - Witamina B6

PL: Witamina B6
EN: Vitamin B6
Pdf: vitamin B6

Oświadczenie (2)

1. Charakterystyka żywności / składnika

The food constituent that is the subject of the health claims is vitamin B6, which is a group of compounds comprising three free forms, pyridoxine, pyridoxal, pyridoxamine, and their 5'-phosphates derivatives (PNP, PLP and PMP). Vitamin B6 occurs naturally in foods, mainly as pyridoxal phosphate (animals), pyridoxine beta-glucoside (plants) and some pyridoxyl peptides (processed foods). Vitamin B6 is a well recognised nutrient and is measurable in foods by established methods.
Vitamin B6 is authorised for addition to foods (Annex I of the Regulation (EC) No 1925/20066 and Annex I of Directive 2002/46/EC7). This evaluation applies to vitamin B6 naturally present in foods and those forms authorised for addition to foods (Annex II of the Regulation (EC) No 1925/2006, and Annex II of Directive 2002/46/EC).
The Panel considers that the food constituent, vitamin B6, which is the subject of the health claims is sufficiently characterised.

2.2. Utrzymanie prawidłowego stanu kości (ID 74)

The claimed effect is “bone/teeth/hair/skin and nail health”. The Panel assumes that the target population is the general population.
The Panel considers that maintenance of normal bone is a beneficial physiological effect.

2.3. Utrzymanie prawidłowego stanu zębów (ID 74)

The claimed effect is “bone/teeth/hair/skin and nail health”. The Panel assumes that the target population is the general population.
The Panel considers that maintenance of normal teeth is a beneficial physiological effect.

2.4. Utrzymanie prawidłowego stanu włosów (ID 74)

The claimed effect is “bone/teeth/hair/skin and nail health”. The Panel assumes that the target population is the general population.
The Panel considers that maintenance of normal hair is a beneficial physiological effect.

2.5. Utrzymanie prawidłowego stanu skóry (ID 74)

The claimed effect is “bone/teeth/hair/skin and nail health”. The Panel assumes that the target population is the general population.
The Panel considers that maintenance of normal skin is a beneficial physiological effect.

2.6. Utrzymanie prawidłowego stanu paznokci (ID 74)

The claimed effect is “bone/teeth/hair/skin and nail health”. The Panel assumes that the target population is the general population.
The Panel considers that maintenance of normal nails is a beneficial physiological effect.

3. Naukowe uzasadnienia wpływu na zdrowie człowieka

Vitamin B6 functions as a coenzyme in a variety of enzymatic reactions in the metabolism of amino acids, one-carbon units, lipids, the pathways of gluconeogenesis, haem, and neurotransmitter biosynthesis (McCormick, 2006; Mackey et al., 2006).

3.2. Utrzymanie prawidłowego stanu kości (ID 74)

A total of 16 references were provided, including six textbooks, two opinions of scientific bodies, one review, five human studies and two other publications. Most of the studies dealt with the role of
10
homocysteine as a putative risk factor for osteoporosis. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the dietary intake of vitamin B6 and maintenance of normal bone.

3.3. Utrzymanie prawidłowego stanu zębów (ID 74)

A total of 16 references were provided, including six textbooks, two opinions of scientific bodies, one review, five human studies and two other publications, on outcomes unrelated to the claimed effect. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the dietary intake of vitamin B6 and maintenance of normal teeth.

3.4. Utrzymanie prawidłowego stanu włosów (ID 74)

A total of 16 references were provided, including six textbooks, two opinions of scientific bodies, one review, five human studies and two other publications, on outcomes unrelated to the claimed effect. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the dietary intake of vitamin B6 and maintenance of normal hair.

3.5. Utrzymanie prawidłowego stanu skóry (ID 74)

A total of 16 references were provided, including six textbooks, two opinions of scientific bodies, one review, five human studies and two other publications. The only reference related to vitamin B6 and skin was a link to a website advising adolescents on their intake of nutrients. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the dietary intake of vitamin B6 and maintenance of normal skin.

3.6. Utrzymanie prawidłowego stanu paznokci (ID 74)

A total of 16 references were provided, including six textbooks, two opinions of scientific bodies, one review, five human studies and two other publications, on outcomes unrelated to the claimed effect. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the dietary intake of vitamin B6 and maintenance of normal nails.

5. Warunki i możliwe ograniczenia stosowania oświadczenia

The Panel considers that in order to bear the claims a food should be at least a source of vitamin B6 as per Annex to Regulation (EC) No 1924/2006. Such amounts can be easily consumed as part of a balanced diet. The target population is the general population. Tolerable Upper Intake Levels (ULs) have been established for vitamin B6 in children, adolescents and adults (SCF, 2000).

Warunki i możliwe ograniczenia stosowania oświadczenia

Must meet minimum requirements for use of the claim "source of [name of vitamin/s] and/or [name of mineral/s}" as per Annex to Regulation 1924/2006. Agency guidance for supplements is that products containing >10 mg of vitamin B6 should carry the label advisory statement "Long term intakes [of this amount of vitamin B6] may lead to mild tingling and numbness"