ID 722 -
Glutamina
PL: Glutamina
EN: Glutamine
Pdf: L-glutamine
1. Charakterystyka żywności / składnika
The food constituent that is the subject of the health claims is L-glutamine.
Glutamine is a conditionally indispensable amino acid provided by mixed dietary protein intakes from different sources. It can also be consumed as a food supplement. The content of L-glutamine in foods can be measured by established methods.
The Panel considers that the food constituent, L-glutamine, which is the subject of the health claims, is sufficiently characterised.
2.1. Wpływ na wzrost i utrzymanie masy mięśniowej (ID 719, 722, 3185)
The claimed effects are “increasing cell swelling/volumization”, “muscle protein metabolism” and “improves muscles metabolism”. The Panel assumes that the target population is the general population.
In the context of the proposed wordings, the Panel assumes that the claimed effects refer to the growth or maintenance of muscle mass. Failure to increase muscle mass during growth and development, and the loss of muscle mass at any age, will reduce muscle strength and power.
The Panel considers that growth or maintenance of muscle mass is a beneficial physiological effect.
3. Naukowe uzasadnienia wpływu na zdrowie człowieka -
The references provided for the scientific substantiation of these claims included textbooks and narrative reviews which did not provide original data for the scientific substantiation of the claim. Human, animal and in vitro studies on food constituents other than L-glutamine alone (e.g. branched- chain aminoacids (BCAA); N-acetyl-cysteine; mixtures of whey protein plus BCAA or arginine plus L-glutamine; mixtures of soy lecithin, sodium dihydrogen phosphate, thiamin, pyridoxine and L- glutamine; mixtures of glycine, niacin, and glutamine), on glutamine given intravenously, on health outcomes (e.g. treatment of chronic disease or pathological conditions, morbidity and mortality in pre- term infants, use in enteral nutrition) unrelated to the claimed effects, or on the effects of intense training on plasma and tissue concentrations of L-glutamine, were also provided. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claims.
3.1. Wpływ na wzrost i utrzymanie masy mięśniowej (ID 719, 722, 3185)
A claim on protein and growth or maintenance of muscle mass has already been assessed with a favourable outcome (EFSA Panel on Dietetic Products Nutrition and Allergies (NDA), 2010).
Glutamine is a component of dietary protein, and both endogenous and exogenous glutamine contribute to protein synthesis.
No references which addressed the effects of L-glutamine consumption on growth or maintenance of muscle mass were provided. No evidence has been provided that L-glutamine in addition to normal protein intake has an additional role in muscle mass.
The Panel concludes that a cause and effect relationship has not been established between the consumption of L-glutamine and growth or maintenance of muscle mass, apart from the well established role of protein on the claimed effect.
Warunki i możliwe ograniczenia stosowania oświadczenia
The product must contain at least 5 gram Glutamine per serving
Claim to be used for foods for active individuals
