ID 662 -
Glutamina
PL: Glutamina
EN: Glutamine
Pdf: L-glutamine
1. Charakterystyka żywności / składnika
The food constituent that is the subject of the health claims is L-glutamine.
Glutamine is a conditionally indispensable amino acid provided by mixed dietary protein intakes from different sources. It can also be consumed as a food supplement. The content of L-glutamine in foods can be measured by established methods.
The Panel considers that the food constituent, L-glutamine, which is the subject of the health claims, is sufficiently characterised.
2.4. Utrzymanie prawidłowego funkcjonowania układu nerwowego (ID 662, 700)
The claimed effect is “nervous system” and “mental health”. The Panel assumes that the target population is the general population.
In the context of the proposed wordings and the clarifications provided by Member States, the Panel assumes that the claimed effects refer to the maintenance of normal neurological function.
The Panel considers that maintenance of normal neurological function is a beneficial physiological effect.
3. Naukowe uzasadnienia wpływu na zdrowie człowieka -
The references provided for the scientific substantiation of these claims included textbooks and narrative reviews which did not provide original data for the scientific substantiation of the claim. Human, animal and in vitro studies on food constituents other than L-glutamine alone (e.g. branched- chain aminoacids (BCAA); N-acetyl-cysteine; mixtures of whey protein plus BCAA or arginine plus L-glutamine; mixtures of soy lecithin, sodium dihydrogen phosphate, thiamin, pyridoxine and L- glutamine; mixtures of glycine, niacin, and glutamine), on glutamine given intravenously, on health outcomes (e.g. treatment of chronic disease or pathological conditions, morbidity and mortality in pre- term infants, use in enteral nutrition) unrelated to the claimed effects, or on the effects of intense training on plasma and tissue concentrations of L-glutamine, were also provided. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claims.
3.4. Utrzymanie prawidłowego funkcjonowania układu nerwowego (ID 662, 700)
No references which addressed the effects of L-glutamine consumption on neurological function were provided.
The Panel concludes that a cause and effect relationship has not been established between the consumption of L-glutamine and maintenance of normal neurological function.
Warunki i możliwe ograniczenia stosowania oświadczenia
225 mg,;15% of the lower (1500 mg) therapeutic dose ;(Martindale pp. 1785-86);