ID 66 -
Witamina B6
PL: Witamina B6
EN: Vitamin B6
Pdf: vitamin B6
Oświadczenie (4)
- Witamina B6 przyczynia się do prawidłowego funkcjonowania układu nerwowego
1. Charakterystyka żywności / składnika
The food constituent that is the subject of the health claims is vitamin B6, which is a group of compounds comprising three free forms, pyridoxine, pyridoxal, pyridoxamine, and their 5'-phosphates derivatives (PNP, PLP and PMP). Vitamin B6 occurs naturally in foods, mainly as pyridoxal phosphate (animals), pyridoxine beta-glucoside (plants), and some pyridoxyl peptides (processed foods), with varied bioavailability as vitamin B6. Vitamin B6 is a well recognised nutrient and is measurable in foods by established methods.
Vitamin B6 it is authorised for addition to foods (Annex I of the Regulation (EC) No 1925/20064 and Annex I of Directive 2002/46/EC5). This evaluation applies to vitamin B6 naturally present in foods and those forms authorised for addition to foods (Annex II of the Regulation (EC) No 1925/2006, and Annex II of Directive 2002/46/EC).
The Panel considers that the food constituent, vitamin B6, which is the subject of the health claims, is sufficiently characterised.
2.2. Funkcjonowanie układu nerwowego (ID 66)
The claimed effect is “nervous system function”. The Panel assumes that the target population is the general population.
The Panel considers that normal function of the nervous system is beneficial to human health.
3. Naukowe uzasadnienia wpływu na zdrowie człowieka
Vitamin B6 functions as a coenzyme in a variety of enzymatic reactions in the metabolism of amino acids, one-carbon units, lipids, the pathways of gluconeogenesis, haem, and neurotransmitter biosynthesis (McCormick, 2006; Mackey, 2006).
3.2. Funkcjonowanie układu nerwowego (ID 66)
The references provided included 11 textbooks and two reports. One of the reports was on pantothenic acid and the other was an opinion on upper levels of vitamin B6.
Vitamin B6 is taken up into the brain via a transport carrier that has not been well described. In humans, vitamin B6 deficiency is rare. However, when identified, it has been associated with increased seizure activity, an effect which can be ameliorated by vitamin B6 (Fernstrom and Fernstrom, 2005).
The Panel concludes that a cause and effect relationship has been established between the dietary intake of vitamin B6 and normal function of the nervous system. However, the evidence provided does not establish that inadequate intake of vitamin B6 leading to an impaired function of the nervous system occurs in the general EU population.
4.2. Funkcjonowanie układu nerwowego (ID 66)
The Panel considers that the following wording reflects the scientific evidence: “Vitamin B6 contributes to the normal function of the nervous system”.
5. Warunki i możliwe ograniczenia stosowania oświadczenia
The Panel considers that in order to bear the claims a food should be at least a source of vitamin B6 as per Annex to Regulation (EC) No 1924/2006. Such amounts can be easily consumed as part of a balanced diet. The target population is the general population. Tolerable Upper Intake Levels (UL) have been established for vitamin B6 in children, adolescents and adults (SCF, 2000).
Warunki i możliwe ograniczenia stosowania oświadczenia
Must at least be a source of vitamin/s as per annex to regulation 1924/2006. Agency guidance for supplements is that products containing >10 mg of vitamin B6 should carry the label advisory statement "Long term intakes [of this amount of vitamin B6] may lead to mild tingling and numbness"
