ID 628 - Kwas dokozaheksaenowy

PL: Kwas dokozaheksaenowy
EN: Docosahexaenoic acid (DHA)
Pdf: docosahexaenoic acid

Oświadczenie (2)

1. Charakterystyka żywności / składnika

The food constituent that is the subject of the health claims is docosahexaenoic acid (DHA), which is a well characterised n-3 long-chain fatty acid that can be quantified in foods by established methods. The absorption of DHA is well documented. This evaluation applies to all sources of DHA in the specified amounts.
The Panel considers that the food constituent, DHA, which is the subject of the health claims is sufficiently characterised.

2.7. Utrzymanie prawidłowej ruchliwości plemników (ID 628)

The claimed effect is “supportive measure for male fertility through providing the motility agent for spermatozoa tails”. The Panel assumes that the target population is the general male population.
The Panel considers that maintenance of normal spermatozoa motility is a beneficial physiological
effect.

3.6. Utrzymanie prawidłowej ruchliwości plemników (ID 628)

Among the references provided for the substantiation of the claimed effect, one study did not address DHA, which is the food constituent that is the subject of the claim. One study evaluated the metabolism of fatty acids in isolated human testicular cells, another study measured the superoxide dismutase and fatty acid content of spermatozoa from normal vs. subfertile subjects and one study investigated the generation of reactive oxygen species by human spermatozoa in response to DHA exposure. The Panel considers that these endpoints are not appropriate endpoints for the claimed effect.
No intervention studies which evaluated the effect of dietary DHA on spermatozoa motility were provided. Five observational studies in humans evaluated associations between the DHA content of spermatozoa related to motility parameters in healthy, sub-fertile men or patients with retinis pigmentosa. The Panel notes that DHA intakes were not reported in these studies and no conclusions can be drawn for the scientific substantiation of the claimed effect.
Two animal studies did not address relevant endpoints and three animal studies evaluated the effect of an intervention with diets containing mixtures of fatty acids on animal semen composition and functional characteristics (including motility) of the semen. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the consumption of DHA and the maintenance of normal spermatozoa motility.

Warunki i możliwe ograniczenia stosowania oświadczenia

At least 220 mg DHA/day, based on a 2000 kcal diet.