ID 530 -
Kwas dokozaheksaenowy, Kwas eikozapentaenowy
PL: Kwas dokozaheksaenowy, Kwas eikozapentaenowy
EN: DHA+EPA - long chain omega 3 fatty acids
Pdf: eicosapentaenoic acid
1. Charakterystyka żywności / składnika
The food constituent which is the subject of the health claims is mixed long-chain n-3 polyunsaturated fatty acids (n-3 LCPUFA), namely docosahexaenoic acid (DHA) in combination with eicosapentaenoic acid (EPA) and, for ID 703, with docosapentaenoic acid (DPA).
The n-3 LCPUFA EPA, DHA and DPA are recognised nutrients and are measurable in foods by established methods. They are well absorbed when consumed in the form of triglycerides. This evaluation applies to EPA, DHA and, for ID 703, DPA from all sources with suitable bioavailability in the specified amounts.
The Panel considers that the food constituent, EPA, DHA and DPA, which is the subject of the health claims, is sufficiently characterised.
2.7. Ochrona skóry przed uszkodzeniem promieniami ultrafioletowymi (UV) (ID 530)
The claimed effect is “skin health”. The Panel assumes that the target population is the general population.
In the context of the proposed wordings and clarifications provided by Member States, the Panel assumes that the claim refers to the protection of the skin from photo-oxidative (UV-induced) damage.
The Panel considers that the protection of the skin from photo-oxidative (UV-induced) damage is a beneficial physiological effect.
3.4. Ochrona skóry przed uszkodzeniem promieniami ultrafioletowymi (UV) (ID 530)
Among the 26 references provided for the scientific substantiation of this claim, most reported on food constituents (e.g. vitamin E) and/or health effects (e.g. coronary heart disease, sudden cardiac death, blood lipids, blood glucose control, infertility, pregnancy, inflammation, psoriasis, non- melanoma skin cancer) unrelated to the claimed effect. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
Two of the references are general reviews on the role of n-3 fatty acids on the pathogenesis of skin cancer (Black and Rhodes, 2006) and photo-protection (Rhodes, 1998) but did not provide original data for the scientific substantiation of the claimed effect.
An open label intervention study in humans on the effects of fish oil supplementation on the minimal erythemal dose of UVB irradiation, and on the threshold UVB irradiation dose for papule provocation in patients with polymorphic light eruption, was presented (Rhodes et al., 1995). The Panel notes that no conclusions can be drawn from this uncontrolled study for the scientific substantiation of the claimed effect.
A double-blind, placebo controlled intervention study was presented on the effects of EPA alone (4 g per day) on a range of indicators of ultraviolet radiation (UVR)-induced responses and damage in humans, as well as on basal and post-UVR oxidative status (Rhodes et al., 2003). The Panel considers that no conclusions can be drawn from this study on EPA alone for the scientific substantiation of a claim on the combination of EPA and DHA.
The Panel concludes that a cause and effect relationship has not been established between the consumption of EPA and DHA and the protection of the skin from photo-oxidative (UV-induced) damage.
Warunki i możliwe ograniczenia stosowania oświadczenia
200-500mg EPA,
50-250mg DHA per day
