ID 365 -
Magnez
PL: Magnez
EN: Magnesium
Pdf: magnesium
Oświadczenie (4)
- Magnez przyczynia się do prawidłowych podziałów komórkowych
1. Charakterystyka żywności / składnika
The food constituent that is the subject of the health claims is magnesium, which is a well recognised nutrient and is measurable in foods by established methods.
Magnesium occurs naturally in foods and is authorised for addition to foods (Annex I of Regulation (EC) No 1925/20064 and Annex I of Directive 2002/46/EC5). This evaluation applies to magnesium naturally present in foods and to those forms authorised for addition to foods (Annex II of the Regulation (EC) No 1925/2006 and Annex II of Directive 2002/46/EC).
The Panel considers that the food constituent, magnesium, which is the subject of the health claims is sufficiently characterised.
2.4. Podziały komórek (ID 365)
The claimed effect is “cell division”. The Panel assumes that the target population is the general population.
The Panel notes that cell division is a crucial process for tissue growth and development and for tissue maintenance through cell turnover.
The Panel considers that normal cell division is beneficial to human health.
3. Naukowe uzasadnienia wpływu na zdrowie człowieka -
Magnesium is an essential nutrient and serves as a cofactor for over 300 enzymes involved in biosynthetic processes. It is part of the Mg-ATP complex, is essential for oxidative phosphorylation and has roles in energy metabolism, mineral homeostasis, calcium metabolism, and neuromuscular and endocrine function (IoM, 1997; SCF, 2001; Volpe, 2006).
In the human body, 50 to 60% of magnesium is located in the bone. Part of it is readily exchangeable with serum and therefore bone represents a magnesium store. The remaining magnesium is mainly intracellular; extracellular magnesium represents only 1% of the total magnesium content of the body.
3.4. Podziały komórek (ID 365)
Magnesium is able to form complexes with nucleic acids. The negatively charged ribose phosphate structure of nucleic acids has a high affinity for magnesium. The resulting stabilisation of numerous ribonucleotides and deoxyribonucleotides induces physicochemical changes that affect DNA maintenance, duplication and transcription (Rude and Shils, 2006).
The Panel concludes that a cause and effect relationship has been established between the dietary intake of magnesium and cell division.
4.4. Podziały komórek (ID 365)
The Panel considers that the following wording reflects the scientific evidence: “Magnesium contributes to normal cell division”.
5. Warunki i możliwe ograniczenia stosowania oświadczenia
The Panel considers that in order to bear the claim a food should be at least a source of magnesium as per Annex to Regulation (EC) No 1924/2006. Such amounts can be easily consumed as part of a balanced diet. The target population is the general population. No Tolerable Upper Intake Levels (UL) have been established for magnesium normally present in food and beverages. An UL of 250 mg Mg/day for older children and adults has been established for readily dissociable magnesium salts and compounds like MgO in nutritional supplements, waters or added to food and beverages (SCF, 2001).
Warunki i możliwe ograniczenia stosowania oświadczenia
See above