ID 2917 -
	
		
			Indolo-3-karbinol
		
		
		
	 
PL: Indolo-3-karbinol
EN: Indole-3-carbinol
Pdf: various food(s)/food constituent(s)
 
        
        
                
1.8. Apoptoza zniszczonych komórek (ID 2917)
                
                
                    The claimed effect is “induction of apoptosis of transformed and damaged cells”. The Panel assumes  that the target population is the general population.
In the context of the clarifications provided by Member States, the Panel assumes that the claimed  effect refers to apoptosis of damaged cells.
The Panel considers that apoptosis of damaged cells is a beneficial physiological effect.
                 
                 
	        
        
        
        
        
                
2.8. Apoptoza zniszczonych komórek (ID 2917)
                
                
                    The reference provided in relation to this claim was one in vitro study which investigated health  outcomes (i.e. induction of the expression of breast cancer susceptibility genes and prostate cancer  cell types) unrelated to the claimed effect. The Panel considers that no conclusions can be drawn from  this reference for the scientific substantiation of the claim.
No human studies which investigated the effects of the food constituent on measures of apoptosis of  damaged cells were provided in relation to the claim evaluated in this section.
The Panel concludes that a cause and effect relationship has not been established between the  consumption of the food constituent which is the subject of the claim evaluated in this section and  apoptosis of damaged cells.
                 
                 
	        
        
        
Warunki i możliwe ograniczenia stosowania oświadczenia
150 - 450mg daily