ID 28 -
Tiamina
PL: Tiamina
EN: Thiamin
Pdf:
Oświadczenie (4)
- Tiamina przyczynia się do prawidłowego pozyskiwania energii w procesach metabolicznych
Oświadczenie (2)
- metabolizmu makroskładników
- metabolizmu energii
1. Charakterystyka żywności / składnika
The food constituent that is the subject of the health claim is thiamine (also named vitamin B1), which is a well recognised nutrient and is measurable in foods by established methods.
Thiamine occurs naturally in foods and is authorised for addition to foods (Annex I of the Regulation (EC) No 1925/20064 and Annex I of Directive 2002/46/EC5). This evaluation applies to thiamine naturally present in foods and those forms authorised for addition to foods (Annex II of the Regulation (EC) No 1925/2006 and Annex II of Directive 2002/46/EC).
The Panel considers that the food constituent, thiamine, which is the subject of the health claims, is sufficiently characterised.
2.1. Metabolizm energetyczny (ID 21, 24, 28)
The claimed effects are related to “energy metabolism” and “macronutrient metabolism”. The Panel assumes that the target population is the general population.
The Panel notes that in the context of the proposed wording, energy metabolism and macronutrient metabolism relates to energy-yielding metabolism of macronutrients.
The Panel considers that normal energy-yielding metabolism is beneficial to human health.
3. Naukowe uzasadnienia wpływu na zdrowie człowieka
Thiamine (as thiamine diphosphate, a co-enzyme for several oxidative decarboxylation reactions and for transketolase) has a central role in energy-yielding metabolism, especially in the metabolism of carbohydrates and of branched-chain amino acids (Bender, 1999; EC, 2003). Thiamine (as thiamine triphosphate), has a function in nerve conduction (Bender, 1999; IoM, 1998). Thiamine deficiency can result in three distinct syndromes: Beriberi, a chronic peripheral neuritis, which may or may not be associated with heart failure and oedema, acute pernicious (fulminating) beriberi, in which heart failure and life-threatening metabolic acidosis predominate, with little or no evidence of peripheral neuritis, and central nervous system disturbances, Wernicke's encephalopathy with Korsakoff's psychosis (SCF, 1993).
3.1. Metabolizm energetyczny (ID 21, 24, 28)
Thiamine is the precursor for thiamine diphosphate, which is a co-enzyme for a number of reactions involved in carbohydrates and of branched-chain amino acids metabolism and central energy-yielding metabolic pathways, e.g. alpha-ketoacid decarboxylation and transketolation reactions.
The Panel concludes that a cause and effect relationship has been established between the dietary intake of thiamine and normal energy-yielding metabolism. However, the evidence provided does not establish that inadequate intake of thiamine leading to impaired energy-yielding metabolism, occurs in the general EU population.
4.1. Metabolizm energetyczny (ID 21, 24, 28)
The Panel considers that the following wording reflects the scientific evidence:
“Thiamine contributes to normal energy-yielding metabolism”.
5. Warunki i możliwe ograniczenia stosowania oświadczenia
The Panel considers that in order to bear the claims a food should be at least a source of thiamine as per Annex to Regulation 1924/2006. Tolerable Upper Intake Levels (UL) have not been established for thiamine in children, adolescents and adults. The target population is the general population.
Warunki i możliwe ograniczenia stosowania oświadczenia
0,7mg/day (equal to 50% of ADI (Acceptable Daily Intake)
The product must contain at least 15% of the RDA
Applicable to both adults and children