ID 279 - Selen

PL: Selen
EN: Selen
Pdf: selenium

Oświadczenie (4)

Oświadczenie (2)

1. Charakterystyka żywności / składnika

The food constituent that is the subject of the health claims is selenium, which is a well recognised nutrient and is measurable in foods by established methods.
Selenium occurs naturally in foods and is authorised for addition to foods and for use in food supplements (Annex I of the Regulation (EC) No 1925/20064 and Annex I of Directive 2002/46/EC5). This evaluation applies to selenium naturally present in foods and to those forms authorised for addition to foods and for use in food supplements (Annex II of the Regulation (EC) No 1925/2006 and Annex II of Directive 2002/46/EC).
The Panel considers that the food constituent, selenium, which is the subject of the health claims is sufficiently characterised.

2.3. Funkcjonowanie tarczycy (ID 279, 282, 286, 1289, 1290, 1291, 1293)

The claimed effects are “thyroid function”, “iodine utilisation”, “thyroid hormone production” and “normal thyroid hormone metabolism”. The Panel assumes that the target population is the general population.
The Panel considers that normal thyroid function is beneficial to human health.

3. Naukowe uzasadnienia wpływu na zdrowie człowieka - 

Selenium is an essential trace element. Twenty-five selenoprotein genes have been identified in the human genome (Kryukov et al., 2003). Selenoproteins have a number of functions, comprising various catalytic roles (glutathione peroxidases, thioredoxin reductases, and iodothyronine
deiodinases), structural roles, detoxifying functions (e.g. selenoprotein P) and storage and transport activities. Selenium is present in foods mainly as selenomethionine and selenocysteine. It is absorbed efficiently by the intestine over a wide range of concentrations and across a variety of different molecular forms (Bates, 2005).

3.3. Funkcjonowanie tarczycy (ID 279, 282, 286, 1289, 1290, 1291, 1293)

Deiodination is a pathway of thyroid hormone metabolism implicated in activation and deactivation of thyroid hormones. The metabolism is catalysed by three iodothyronine deiodinases (D1-3) which are homologous selenoproteins. In humans the enzymes are found in various tissues; D1 and D2 but not D3 also occur in the thyroid gland (Kuiper et al., 2005). Thus, the known biological functions of selenium include regulation of thyroid hormone action. 2005).
The Panel concludes that a cause and effect relationship has been established between the dietary intake of selenium and normal thyroid function. However, the evidence provided does not establish that inadequate intake of selenium leading to impaired thyroid function occurs in the general EU population.

4.3. Funkcjonowanie tarczycy (ID 279, 282, 286, 1289, 1290, 1291, 1293)

The Panel considers that the following wording reflects the scientific evidence: “selenium contributes to normal thyroid function”.

5. Warunki i możliwe ograniczenia stosowania oświadczenia

The Panel considers that in order to bear the claims a food should be at least a source of selenium as per Annex to Regulation (EC) No 1924/2006. Such amounts can be easily consumed as part of a balanced diet. The target population is the general population. Tolerable Upper Intake Levels (UL) have been established as 300 µg/day for adults and for pregnant and lactating woman. For children and adolescents UL were established as 60 µg/day for 1-3 years, 90 µg/day for 4-6 years, 130 µg/day for 7-10 years, 200 µg/day for 11-14 years and 250 µg/day for 15-17 years (SCF, 2000).

Warunki i możliwe ograniczenia stosowania oświadczenia

Must at least be a source of mineral/s as per annex to regulation 1924/2006