ID 216 -
Witamina E
PL: Witamina E
EN: Vitamin E
Pdf:
1. Charakterystyka żywności / składnika
The food constituent that is the subject of the health claims is vitamin E, which is a well recognised nutrient and is measurable in foods by established methods.
Vitamin E is authorised for addition to foods (Annex I of the Regulation (EC) No 1925/20066 and Annex I of Directive 2002/46/EC7). This evaluation applies to vitamin E naturally present in foods and those forms authorised for addition to foods (Annex II of Regulation (EC) No 1925/2006 and Annex II of Directive 2002/46/EC).
The Panel considers that the food constituent, vitamin E, which is the subject of the health claims, is sufficiently characterised.
2.12. Utrzymanie prawidłowego krążenia krwi (ID 216)
The claimed effect is “blood circulation”. The Panel assumes that the target population is the general population.
The Panel considers that maintenance of normal blood circulation is a beneficial physiological effect.
3. Naukowe uzasadnienia wpływu na zdrowie człowieka
The evidence provided by opinions/reports from authoritative bodies and reviews shows that there is good consensus on the role of vitamin E in the body (Berdanier et al., 2002; EVM, 2002; Gibney et al., 2002; IoM, 2000; NNR, 2004; Sadler et al., 1999; SCF, 2003; Shils et al., 2006). Vitamin E is fat-soluble and is transported in plasma lipoproteins and partitions into membranes and fat-storage sites where it has the unique role of protecting polyunsaturated fatty acids from peroxidation. Plasma
-tocopherol is regulated by the liver -tocopherol transfer protein ( -TTP). In humans, a genetic
defect in -TTP results in severe vitamin E deficiency (Shils et al., 2006).
A major vitamin E deficiency symptom in humans is peripheral neuropathy characterised by the degeneration of the large calibre axons in the sensory neurons (IoM, 2000). Vitamin E deficiency as a result of inadequate intake of vitamin E is uncommon. Vitamin E deficiency can occur as a result of
genetic abnormalities in -TTP and as a result of various fat malabsorption syndromes. Vitamin E supplementation halts the progression of the neurological abnormalities caused by inadequate nerve
tissue -tocopherol and, in some cases, has reversed these abnormalities. Other vitamin E deficiency symptoms observed in humans include spinocerebellar ataxia, skeleton myopathy, pigmented retinopathy (IoM, 2000), loss of deep tendon reflexes, unsteady gait, restriction of upward gaze and visual field loss (Sadler et al., 1999).
3.12. Utrzymanie prawidłowego krążenia krwi (ID 216)
One study was provided in the consolidated list in relation to vitamin E and blood circulation (Bursell et al., 1999). This study was a randomised, double-blind, placebo-controlled cross-over trial in type 1 diabetic subjects. The aim of this study was to measure retinal blood flow and renal function. The Panel considers that the evidence provided does not establish that patients with diabetes are representative of the general population with regard to retinal blood flow and renal function, or that results obtained in studies on subjects with diabetes can be extrapolated to the general population with regard to retinal blood flow and renal function owing to the abnormal eye and kidney functions of diabetic subjects.
The Panel concludes that a cause and effect relationship has not been established between the dietary intake of vitamin E and maintenance of normal blood circulation.
5. Warunki i możliwe ograniczenia stosowania oświadczenia
The Panel considers that in order to bear the claim a food should be at least a source of Vitamin E as per Annex to Regulation (EC) No 1924/2006. Such amounts can be easily consumed as part of a balanced diet. The target population is the general population. Tolerable Upper Intake Levels (UL) have been established for vitamin E in children, adolescents and adults (SCF, 2003).
Warunki i możliwe ograniczenia stosowania oświadczenia
