ID 1962 -
Kwasy chlorogenowe z kawy
PL: Kwasy chlorogenowe z kawy
EN: Chlorogenic acids from Coffee
Pdf:
1. Charakterystyka żywności / składnika
The foods/food constituents that are the subjects of the health claims are coffee, Coffea Arabica L., chlorogenic acids from coffee, and antioxidants in coffee.
Coffee contains a wide range of “bioactive” compounds including caffeine and other purine derivatives, polyphenolic compounds such as chlorogenic acid derivatives and its degradation product caffeic acid, and specific diterpenes such as kahweol and cafestol. No information is provided on the concentration of such compounds in coffee, but this will likely depend on the coffee variety, on the roasting of the beans and on the brewing process, such as the use of coffee filters. Also, no specifications were provided on the compounds or molecules generically referred to as “antioxidants in coffee”.
The Panel notes that chlorogenic acid from coffee has been specified as the “active” food constituent responsible for the claimed effects considered in this opinion. Chlorogenic acids from coffee are well defined compounds which can be measured in foods by established methods.
The Panel considers that whereas the food/food constituents, coffee and antioxidants in coffee, are not sufficiently characterised in relation to the claimed effects evaluated in this opinion, the food constituent, chlorogenic acids from coffee, is sufficiently characterised.
2.2. Utrzymanie prawidłowego stężenia glukozy we krwi (ID 1100, 1962)
The claimed effect is “glucose homeostasis”. The Panel assumes that the target population is the general population.
In the context of the proposed wordings, the Panel assumes that the claimed effect refers to the long-term maintenance of normal blood glucose concentrations.
The Panel considers that long-term maintenance of normal blood glucose concentrations is a beneficial physiological effect.
3.2. Utrzymanie prawidłowego stężenia glukozy we krwi (ID 1100, 1962)
Some of the references provided for the substantiation of the claim reported on the association between coffee drinking and disease risk (e.g. type II diabetes, gestational diabetes, metabolic disease, cardiovascular disease) in observational (cohort) studies, and on the effects of chlorogenic acids on various aspects of glucose metabolism (enzymes and transporter proteins). Other references included reviews on the dietary sources of chlorogenic acids, and on magnesium supplementation in diabetes. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
Five references reported on human intervention studies which investigated the effects of coffee consumption on either post-prandial glycaemic and insulinaemic responses (Battram et al., 2006; Feinberg et al., 1968; Johnston et al., 2003; Keijzers et al., 2002), or on plasma C-peptide
concentrations (Wu et al., 2005). The Panel considers that no conclusions can be drawn from these outcome measures in relation to the long-term maintenance of normal blood glucose concentrations.
Two references reported on human intervention studies which addressed the effects of coffee consumption during two to four weeks on fasting glucose and insulin concentrations (Naismith et al., 1970; van Dam et al., 2004). Another reference reported on a cross-sectional study which investigated the association between coffee intake and glucose tolerance and insulin secretion during an oral glucose tolerance test (Bidel et al., 2006). In all of these studies, coffee was not sufficiently characterised in relation to the claimed effect, and outcome measures were not appropriate to assess the long-term maintenance of normal blood glucose concentrations. The Panel considers that no conclusions can be drawn from these studies for the scientific substantiation of the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the consumption of chlorogenic acids from coffee and maintenance of normal blood glucose concentrations.
Warunki i możliwe ograniczenia stosowania oświadczenia
400 mg/day coffee extract containing 45% chlorogenic acids
