ID 1928 -
Tyrozyna
PL: Tyrozyna
EN: L-Tyrosine
Pdf: L-tyrosine
1. Charakterystyka żywności / składnika
The food constituent that is the subject of the health claims is L-tyrosine.
L-Tyrosine is a conditionally indispensable amino acid which occurs naturally in foods, mainly as part of proteins. Dietary L-tyrosine is provided by mixed dietary protein intakes from different sources; it can also be consumed in the form of food supplements. The content of L-tyrosine in foods can be measured by established methods.
The Panel considers that the food constituent, L-tyrosine, is sufficiently characterised.
2.1. Udział w prawidłowej syntezie katecholamin (ID 1928)
The claimed effect is “L-tyrosine is the ultimate precursor of neurotransmitters”. The Panel assumes that the target population is the general population.
In the context of the references provided, the Panel assumes that the claimed effect relates to the normal synthesis of catecholamines.
The Panel considers that contribution to normal synthesis of catecholamines is a beneficial physiological effect.
3.1. Udział w prawidłowej syntezie katecholamin (ID 1928)
L-Tyrosine is the starting point for the synthesis of all catecholamines. L-Tyrosine is hydroxylated to form dihydroxy-L-phenylalanine (also known as levodopa or L-dopa) via the enzyme tyrosine hydroxylase. In dopaminergic neurons, L-dopa is metabolised to dopamine by means of the enzyme dopa decarboxylase. In noradrenergic nerve cells and in the adrenal medulla, dopamine is transformed to noradrenaline via the enzyme dopamine β-hydroxylase. Noradrenaline can then be transformed into adrenaline by the addition of a methyl group through the action of phenylethanolamine-N- methyltransferase (Friedhoff and Silva, 2002).
The Panel concludes that a cause and effect relationship has been established between the consumption of L-tyrosine in a protein adequate diet and contribution to normal synthesis of catecholamines. However, no evidence has been provided that the protein supply in the diet of the European population is not sufficient to fulfil this function of the amino acid.
4.1. Udział w prawidłowej syntezie katecholamin (ID 1928)
The Panel considers that the following wording reflects the scientific evidence: “L-Tyrosine contributes to normal synthesis of catecholamines”.
5.1. Udział w prawidłowej syntezie katecholamin (ID 1928)
The Panel considers that in order to bear the claim a food should be at least a source of protein as per Annex to Regulation (EC) No 1924/2006. Such amounts can be easily consumed as part of a balanced diet. The target population is the general population.
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