ID 1826 - Karnozyna

PL: Karnozyna
EN: L-carnosine
Pdf: L-carnosine

Oświadczenie (2)

1. Charakterystyka żywności / składnika

The food constituent that is the subject of the health claims is L-carnosine.
L-carnosine (C9H14N4O3, molecular weight 226) is a colourless, crystalline dipeptide that is synthesised in the body from the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues, and is found in the skeletal musculature of most vertebrates.
The Panel considers that the food constituent, L-carnosine, which is the subject of the health claims, is sufficiently characterised.

2.4. Utrzymanie prawidłowego funkcjonowania serca (ID 1826)

The claimed effect is “cardiovascular system”. The Panel assumes that the target population is the general population.
In the context of the proposed wording, the Panel assumes that the claimed effect refers to the maintenance of normal cardiac function.
The Panel considers that maintenance of normal cardiac function is a beneficial physiological effect.

3.3. Utrzymanie prawidłowego funkcjonowania serca (ID 1826)

A total of three publications were provided in relation to this claim. These publications included two narrative reviews on the antioxidant properties of carnosine and one narrative review on in vivo and in vitro investigations on the role of carnosine as a modulator of calcium-regulated proteins in cardiac muscle cells, and consequently on the contractility of cardiac muscle. The references provided did not address the effects of oral consumption of L-carnosine on maintenance of normal cardiac function in humans. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the consumption of L-carnosine and maintenance of normal cardiac function.

Warunki i możliwe ograniczenia stosowania oświadczenia

Food supplement with 130-600mg of L-carnosine in the daily dose.