ID 1824 - Karnozyna

PL: Karnozyna
EN: L-carnosine
Pdf: L-carnosine

Oświadczenie (2)

1. Charakterystyka żywności / składnika

The food constituent that is the subject of the health claims is L-carnosine.
L-carnosine (C9H14N4O3, molecular weight 226) is a colourless, crystalline dipeptide that is synthesised in the body from the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues, and is found in the skeletal musculature of most vertebrates.
The Panel considers that the food constituent, L-carnosine, which is the subject of the health claims, is sufficiently characterised.

2.1. Zwiększenie siły mięśni (ID 1824)

The claimed effect is “physical performance and condition”. The Panel assumes that the target population is active individuals in the general population.
In the context of the proposed wording, the Panel assumes that the claimed effect refers to muscle power. Muscle power can be defined as the ability of the neuromuscular system to produce high forces at high velocity. Muscle power is an important component of physical performance and functional capacity, especially in exercises which require explosive strength such as the long jump and the high jump.
The Panel considers that an increase in muscle power is a beneficial physiological effect.

2.2. Wzrost wytrzymałości (ID 1824)

The claimed effect is “physical performance and condition”. The Panel assumes that the target population is individuals performing endurance exercise.
In the context of the proposed wording, the Panel assumes that the claimed effect refers to an enhanced endurance capacity. Endurance capacity refers to the time to self-assessed fatigue when exercising at a constant workload or speed.
The Panel considers that an increase in endurance capacity is a beneficial physiological effect.

3.1. Zwiększenie siły mięśni (ID 1824)

A total of three publications were provided in relation to this claim. These publications included two narrative reviews on the antioxidant properties of carnosine and one narrative review on the role of carnosine as a modulator of calcium-regulated proteins in cardiac muscle cells. The references provided did not address the effects of oral consumption of L-carnosine on increase in muscle power. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the consumption of L-carnosine and an increase in muscle power.

3.2. Wzrost wytrzymałości (ID 1824)

A total of three publications were provided in relation to this claim. These publications included two narrative reviews on the antioxidant properties of carnosine and one narrative review on the role of carnosine as a modulator of calcium-regulated proteins in cardiac muscle cells. The references provided did not address the effects of oral consumption of L-carnosine on increase in endurance capacity. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the consumption of L-carnosine and an increase in endurance capacity.

Warunki i możliwe ograniczenia stosowania oświadczenia

Food supplement with 130-600mg of L-carnosine in the daily dose.