ID 1759 - Cynk

PL: Cynk
EN: Zink
Pdf: zinc

Oświadczenie (4)

Oświadczenie (2)

1. Charakterystyka żywności / składnika

The food constituent that is the subject of the claims is zinc, which is a well recognized nutrient and is measurable in foods by established methods. Zinc occurs naturally in foods and is authorised for addition to foods (Annex I of the Regulation (EC) No 1925/20064 and Annex I of Directive 2002/46/EC5). This evaluation applies to zinc naturally present in foods and those forms authorised for addition to foods (Annex II of the Regulation (EC) No 1925/2006 and Annex II of Directive 2002/46/EC).
The Panel considers that the food constituent, zinc, which is the subject of the health claims, is sufficiently characterised.

2.2. Synteza DNA i podziały komórek (ID 292, 1759)

The claimed effect is “DNA synthesis / cell division”. The Panel assumes that the target population is the general population.
The Panel notes that DNA synthesis and cell division are crucial processes for tissue growth and development and for tissue maintenance through cell turnover.
The Panel considers that normal DNA synthesis and cell division are beneficial to human health.

3. Naukowe uzasadnienia wpływu na zdrowie człowieka - 

Zinc is present in all tissues. It has essential structural, regulatory or catalytic roles in many enzymes. It maintains the configuration of a number of non-enzymatic proteins such as pre-secretory granules of insulin, some mammalian gene transcription proteins and thymulin. It facilitates hormone and receptor binding at membrane and nuclear levels, and it may maintain integrity of biomembranes. Consequently zinc participates in gene expression and in the mechanisms and control of major metabolic pathways involving proteins, carbohydrates, nucleic acids and lipids (SCF, 1993; DoH, 1991). Human zinc deficiency symptoms include retarded growth, depressed immune function, skin lesions, skeletal abnormalities, impaired reproductive ability and behavioural abnormalities such as changes in mood, loss of affect and emotional lability, anorexia, dysfunction of smell and taste, irritability and depression (SCF, 2003; EVM, 2002, Cousins, 2006).

3.2. Synteza DNA i podziały komórek (ID 292, 1759)

Zinc has essential structural, regulatory or catalytic roles in many enzymes. Zinc plays a role in the stabilization of genetic material and is an essential component of some enzymes that participate in the synthesis of nucleic acids. About 1% of human genome codes for zinc finger proteins that play an important regulatory function in gene expression Zinc inadequacy affects gene expression, DNA or RNA metabolism and impairs cell division (Freake, 2006; EVM, 2002; King and Cousins, 2006; IoM, 2001).
The Panel concludes that a cause and effect relationship has been established between the dietary intake of zinc and normal DNA synthesis and cell division. However, the evidence provided does not establish that inadequate intake of zinc leading to impaired DNA synthesis and cell division occurs in the general EU population.

4.2. Synteza DNA i podziały komórek (ID 292, 1759)

The Panel considers that the following wording reflects the scientific evidence: “Zinc contributes to normal DNA synthesis and cell division”.

5. Warunki i możliwe ograniczenia stosowania oświadczenia

The Panel considers that in order to bear the claim a food should be at least a source of zinc as per Annex to Regulation (EC) No 1924/2006. The target population is the general population. Such amounts can be easily consumed as part of a balanced diet. Tolerable Upper Intake Levels (UL) have been established for zinc as 25 mg/day in adults and to pregnant and lactating woman. For children and adolescents UL was established as 7 mg/day for 1-3 years, 10 mg/day for 4-6 years, 13 mg/day for 7-10 years, 18 mg/day for 11-14 years and 22 mg/day for 15-17 years (SCF 2003).

Warunki i możliwe ograniczenia stosowania oświadczenia

15% RDA/day = 2,25 mg Zn ; 390 mg powder supports 15% RDA for Zn and 55% RDA for Cu ; Dayly Total Dose Zn = 25 mg/day