ID 1575 -
5-hydroksytryptofan
PL: 5-hydroksytryptofan
EN: 5-HTP
Pdf: 5-hydroxytryptophan
1. Charakterystyka żywności / składnika
The food constituent that is the subject of the health claim is “5-hydroxytryptophan”.
5-Hydroxytryptophan is naturally present in food and can be measured by established methods.
The Panel considers that the food constituent, 5-hydroxytryptophan, which is the subject of the health claim is sufficiently characterised.
2.1. Poprawa nastroju (ID 1575)
The claimed effect is “mood enhancement”. The Panel assumes that the target population is the general population.
Enhancement of mood is measurable by established methods.
The Panel considers that enhancement of mood might be beneficial to human health.
3.1. Poprawa nastroju (ID 1575)
Three references were cited to substantiate the claim. One was a narrative review, another was a Cochrane review of studies on various forms of clinically depressed patients. The third was a study of the effects of 5-HTP in combination with chlorimipramine in clinically depressed patients. The Panel notes that the evidence provided does not establish that clinically depressed patients are representative of the general population with regard to mood enhancement, or that results obtained in studies with clinically depressed subjects can be extrapolated to mood enhancement in the general population.
The Panel concludes that a cause and effect relationship has not been established between the dietary intake of 5-HTP and mood enhancement.
Warunki i możliwe ograniczenia stosowania oświadczenia
The strongest research study used 300mg daily.
To also present a statement indicating caution with doses of over 600mg, which may cause gastrointestinal upset. 5-HTP increases serotonin levels, caution should be exercised if used along-side anti-depressants
