ID 1559 -
Glukomannan
PL: Glukomannan
EN: Glucomanan
Pdf: konjac mannan
Oświadczenie (2)
- zmniejszenie glikemii odpowiedzi
1. Charakterystyka żywności / składnika
The food constituent that is the subject of the health claims is glucomannan. Glucomannan (konjac mannan) is a water-soluble type of fibre composed of a straight chain of β-1→4 D-mannose and D- glucose units in a ratio of 1.6:1 with a small amount of branching (8 %) through β-(1→6)-glucosyl linkages. It is derived from the tuberous roots of the konjac plant (Amorphophallus konjac K. Koch). Glucomannan is non-digestible in the human small intestine. It has a high molecular weight (200-2000 kDa) and high viscosity in water solution. Glucomannan does not occur naturally in foods. It is a food additive used as an emulsifier and a thickener, and is also consumed in the form of food supplements (Katsuraya et al., 2003).
The Panel considers that the food constituent, konjac mannan (glucomannan), which is the subject of the health claims, is sufficiently characterised.
2.2. Zmniejszenie stężenia glukozy we krwi po posiłku (ID 1559)
The claimed effect is “reduction of glycaemic response”. The Panel assumes that the target population is individuals willing to reduce their post-prandial glycaemic responses.
In the context of the proposed wordings, the Panel assumes that the claimed effect refers to the reduction of post-prandial glycaemic responses.
Postprandial glycaemia is interpreted as the elevation of blood glucose concentrations after consumption of a food and/or meal. This is a normal physiological response that varies in magnitude and duration and may be influenced by the chemical and physical nature of the food or meal consumed, as well as by individual factors (Venn and Green, 2007). The evidence provided does not establish that decreasing post-prandial glycaemic responses in subjects with normal glucose tolerance is a beneficial physiological effect. However, it may be beneficial to subjects with impaired glucose tolerance as long as post-prandial insulinaemic responses are not disproportionally increased. Impaired glucose tolerance and hyperinsulinaemia are common in the general population of adults.
The Panel considers that the reduction of post-prandial glycaemic responses may be a beneficial physiological effect.
3.2. Zmniejszenie stężenia glukozy we krwi po posiłku (ID 1559)
A total of 10 references were submitted in relation to this claim. Six were textbooks and consensus opinions in relation to the health effects of dietary fibre in general, one was a narrative review on the health effects of dietary fibre in general, one was a narrative review on the potential health effects of glucomannan and two reported on human intervention studies investigating the effects of glucomannan on health outcomes other than post-prandial glycaemic responses (e.g. fasting plasma and glucose concentrations, long-term blood glucose control). Also, some intervention studies on the effects of glucomannan on post-prandial glycaemic responses in type 2 diabetic subjects under pharmacological treatment for hyperglycaemia have been cited in relation to other claims on glucomannan. The Panel considers that no conclusions can be drawn from these references for the scientific substantiation of the claimed effect.
One reference submitted (Magnati et al., 1984) reported on a randomised, placebo-controlled, cross- over intervention investigating the effects of glucomannan on post-prandial blood glucose responses during an oral glucose tolerance test (OGTT) with 75 g glucose in 24 obese normoglycaemic subjects (19 females). No measures of insulin responses were reported. The Panel considers that no conclusions can be drawn from this study for the scientific substantiation of the claimed effect.
The Panel concludes that a cause and effect relationship has not been established between the consumption of glucomannan and the reduction of post-prandial glycaemic responses.
Warunki i możliwe ograniczenia stosowania oświadczenia
2.5-5.0 g / day